115416-38-1
Chemical Structure
5-(Biotinamido)pentylamine
- CAS No.: 115416-38-1
- Formula:C15H28N4O2S
- Molecular Weight:328.47
IUPAC Name: N-(5-aminopentyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
InChIKey: CCSGGWGTGOLEHK-OBJOEFQTSA-N
SMILES: O=C(NCCCCCN)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
Biological Activity: 5-(Biotinamido)pentylamine is an amine donor substrate for transglutaminase. 5-(Biotinamido)pentylamine can be used as a biotin-labeled probe to specifically participate in the calcium-dependent reaction catalyzed by TG, bind to the γ-carboxamide group of the glutamine residue in the protein, introduce the biotin tag into the target protein, and form a biotinylated protein product. 5-(Biotinamido)pentylamine can be used for the labeling, separation, and detection of TG amine receptor protein substrates[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-(Biotinamido)pentylamine | 99.96% | 5-(Biotinamido)pentylamine is an amine donor substrate for transglutaminase. 5-(Biotinamido)pentylamine can be used as a biotin-labeled probe to specifically participate in the calcium-dependent reaction catalyzed by TG, bind to the γ-carboxamide group of the glutamine residue in the protein, introduce the biotin tag into the target protein, and form a biotinylated protein product. 5-(Biotinamido)pentylamine can be used for the labeling, separation, and detection of TG amine receptor protein substrates. | ||||||||||||||||||||
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References
- [1]. Ikura K, et al. Identification of amine acceptor protein substrates of transglutaminase in liver extracts: use of 5-(biotinamido) pentylamine as a probe. Arch Biochem Biophys. 1998 Aug 15;356(2):280-6. [Content Brief]
- [2]. Singh RN, et al. Detection of the amine acceptor protein substrates of transglutaminase with 5-(biotinamido) pentylamine. Anal Biochem. 1995 Oct 10;231(1):261-3. [Content Brief]
- [3]. Ichikawa A, et al. Identification of new amine acceptor protein substrate candidates of transglutaminase in rat liver extract: use of 5-(biotinamido) pentylamine as a probe. Biosci Biotechnol Biochem. 2008 Apr;72(4):1056-62. [Content Brief]
