1155361-01-5
Chemical Structure
Antifungal agent-162
- CAS No.: 1155361-01-5
- Formula:C21H21F3N4O
- Molecular Weight:402.42
IUPAC Name: 1-(allyl(3-fluorobenzyl)amino)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol
InChIKey: HVGVWTUVQVPWKH-UHFFFAOYSA-N
SMILES: FC1=CC=CC(=C1)CN(CC=C)CC(O)(C2=CC=C(F)C=C2F)CN3N=CN=C3
Biological Activity: Antifungal agent-162 (Compound 1c) is an Antifungal agent. Antifungal agent-162 exhibits potent in vitro antifungal activity against Candida albicans, Cryptococcus neoformans, Candida parapsilosis, Candida tropicalis, Candida krusei, and Microsporum gypseum (with MIC80 values ranging from 0.0156 to 0.25 μg/mL), while shows no activity against Aspergillus fumigatus[1].
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Antifungal agent-162 | Antifungal agent-162 (Compound 1c) is an Antifungal agent. Antifungal agent-162 exhibits potent in vitro antifungal activity against Candida albicans, Cryptococcus neoformans, Candida parapsilosis, Candida tropicalis, Candida krusei, and Microsporum gypseum (with MIC80 values ranging from 0.0156 to 0.25 μg/mL), while shows no activity against Aspergillus fumigatus. | |||||||||||||||||||||
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