115750-37-3
115750-37-3
Chemical Structure
KW-3407
- CAS No.: 115750-37-3
- Formula:C20H27N3O2.3/2C4H4O4
- Molecular Weight:515.56
SMILES: CCN(CC)CCNC1C2=CC(OC)=CC=C2OCC3=NC=CC=C31.O=C(O)/C=C/C(O)=O.[3/2]
Biological Activity: KW-3407 is an antiarrhythmic agent. KW-3407 can inhibit two-stage (24 and 48 h) coronary ligation-, digitalis- and adrenaline-induced spontaneously occurring arrhythmias with IC50 values of 18.1, 14.4, 18.3 and 21.4 μg/mL. KW-3407 can decrease the sinoatrial rate and contractile force, and increase the coronary blood flow and AV conduction times[1].
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KW-3407 | KW-3407 is an antiarrhythmic agent. KW-3407 can inhibit two-stage (24 and 48 h) coronary ligation-, digitalis- and adrenaline-induced spontaneously occurring arrhythmias with IC50 values of 18.1, 14.4, 18.3 and 21.4 μg/mL. KW-3407 can decrease the sinoatrial rate and contractile force, and increase the coronary blood flow and AV conduction times. | |||||||||||||||||||||
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