1159996-43-6
1159996-43-6
Chemical Structure
AMG8788
- CAS No.: 1159996-43-6
- Formula:C23H18F4N2O
- Molecular Weight:414.40
IUPAC Name: (R)-N-(4-fluorophenyl)-1-(4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide
InChIKey: ADCDUDFEGFKKQH-OAQYLSRUSA-N
SMILES: O=C(N1CCC2=C(C=CC=C2)[C@H]1C3=CC=C(C(F)(F)F)C=C3)NC4=CC=C(F)C=C4
Biological Activity: AMG8788 is a potent, selective, orally active antagonist of TRPM8 with an IC50 of 63.2 nM[1].
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AMG8788 | AMG8788 is a potent, selective, orally active antagonist of TRPM8 with an IC50 of 63.2 nM. | |||||||||||||||||||||
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