1170354-22-9
Chemical Structure
Difluorinated Curcumin
Synonym(s): 3,4-Difluorobenzylidene curcumin
- CAS No.: 1170354-22-9
- Formula:C28H22F2O6
- Molecular Weight:492.47
IUPAC Name: (1E,6E)-4-(3,4-difluorobenzylidene)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
InChIKey: UUPCLOLPGXQUSO-LUZURFALSA-N
SMILES: FC(C=C1/C=C(C(/C=C/C2=CC(OC)=C(C=C2)O)=O)/C(/C=C/C3=CC(OC)=C(C=C3)O)=O)=C(C=C1)F
Biological Activity: Difluorinated Curcumin (3,4-Difluorobenzylidene curcumin) is a fluorinated curcumin analog with high bioavailability and anticancer activity. Difluorinated Curcumin inhibits the self-renewal ability of tumor stem/stem-like cells, clonogenicity, invasiveness and angiogenesis of tumor cells. Difluorinated Curcumin also increases cell sensitivity to chemotherapy[1].
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Difluorinated Curcumin | 99.56% | Difluorinated Curcumin (3,4-Difluorobenzylidene curcumin) is a fluorinated curcumin analog with high bioavailability and anticancer activity. Difluorinated Curcumin inhibits the self-renewal ability of tumor stem/stem-like cells, clonogenicity, invasiveness and angiogenesis of tumor cells. Difluorinated Curcumin also increases cell sensitivity to chemotherapy. | ||||||||||||||||||||
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