117089-08-4
117089-08-4
Chemical Structure
FW1256
- CAS No.: 117089-08-4
- Formula:C12H10NOPS
- Molecular Weight:247.25
IUPAC Name: 2-phenyl-3H-benzo[d][1,3,2]oxazaphosphole 2-sulfide
InChIKey: AXFLRXAQPCLTEA-UHFFFAOYSA-N
SMILES: S=P1(OC2=CC=CC=C2N1)C3=CC=CC=C3
Biological Activity: FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FW1256 | 95.0% | FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment. | ||||||||||||||||||||
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References
- [1]. Huang CW, et al. A novel slow-releasing hydrogen sulfide donor, FW1256, exerts anti-inflammatory effects in mouse macrophages and in vivo. Pharmacol Res. 2016 Nov;113(Pt A):533-546. [Content Brief]
- [2]. Feng W, et al. Discovery of New H2S Releasing Phosphordithioates and 2,3-Dihydro-2-phenyl-2-sulfanylenebenzo[d][1,3,2]oxazaphospholes with Improved Antiproliferative Activity. J Med Chem. 2015 Aug 27;58(16):6456-80. [Content Brief]
