1173900-37-2
1173900-37-2
Chemical Structure
(S)-AZD 6482
Synonym(s): (S)-KIN-193
- CAS No.: 1173900-37-2
- Formula:C22H24N4O4
- Molecular Weight:408.45
IUPAC Name: (S)-2-((1-(7-methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethyl)amino)benzoic acid
InChIKey: IRTDIKMSKMREGO-HNNXBMFYSA-N
SMILES: O=C(C1=CC=CC=C1N[C@@H](C)C2=CC(C)=CN3C2=NC(N4CCOCC4)=CC3=O)O
Biological Activity: (S)-AZD6482 ((S)-KIN-193) is a highly effective and selective ATP-competitive inhibitor of PI3Kβ, exhibiting an IC(50) of 0.01 μM, and it can reduce insulin-induced glucose uptake by human adipocytes in vitro with an IC(50) of 4.4 μM.
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(S)-AZD 6482 | (S)-AZD6482 ((S)-KIN-193) is a highly effective and selective ATP-competitive inhibitor of PI3Kβ, exhibiting an IC(50) of 0.01 μM, and it can reduce insulin-induced glucose uptake by human adipocytes in vitro with an IC(50) of 4.4 μM. | |||||||||||||||||||||
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