117574-40-0
117574-40-0
Chemical Structure
CV-6504
- CAS No.: 117574-40-0
- Formula:C15H15NO2
- Molecular Weight:241.29
IUPAC Name: 2,3,5-trimethyl-6-(pyridin-3-ylmethyl)cyclohexa-2,5-diene-1,4-dione
InChIKey: IPGAFOVEIIWXFR-UHFFFAOYSA-N
SMILES: O=C1C(C)=C(C)C(C(C)=C1CC2=CC=CN=C2)=O
Biological Activity: CV-6504 is a dual inhibitor of TXA2 synthase and 5-lipoxygenase. CV-6504 can scavenge ROS and exhibit antitumor activity. CV-6504 can be used for the researches of cancer, inflammation and cardiovascular disease[1][2].
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CV-6504 | CV-6504 is a dual inhibitor of TXA2 synthase and 5-lipoxygenase. CV-6504 can scavenge ROS and exhibit antitumor activity. CV-6504 can be used for the researches of cancer, inflammation and cardiovascular disease. | |||||||||||||||||||||
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References
- [1]. Terao S, et al. Synthesis and biological evaluation of 2,3,5-trimethyl-6-(3-pyridylmethyl)-1,4-benzoquinone (CV-6504), a dual inhibitor of TXA2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species (AOS). Adv Prostaglandin Thromboxane Leukot Res. 1991;21A:173-6. [Content Brief]
- [2]. Hussey HJ, et al. Mechanism of the anti-tumour effect of 2,3,5-trimethyl-6-(3-pyridylmethyl) 1,4-benzoquinone (CV-6504). Br J Cancer. 1997;75(6):845-9. [Content Brief]
