1176-09-6
1176-09-6
Chemical Structure
Raptinal
- CAS No.: 1176-09-6
- Formula:C28H18O2
- Molecular Weight:386.44
IUPAC Name: 9H,9'H-[9,9'-bifluorene]-9,9'-dicarbaldehyde
InChIKey: GLANOOJJBKXTMI-UHFFFAOYSA-N
SMILES: O=CC1(C2(C=O)C3=C(C4=C2C=CC=C4)C=CC=C3)C5=C(C6=C1C=CC=C6)C=CC=C5
Biological Activity: Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Raptinal | 99.54% | Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9. | ||||||||||||||||||||
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References
- [1]. Yanheng Chen, et al. H. pylori infection confers resistance to apoptosis via Brd4-dependent BIRC3 eRNA synthesis. Cell Death Dis. 2020 Aug 21;11(8):667. [Content Brief]
- [2]. Rahul Palchaudhuri,et al. A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed. Cell Rep. 2015 Dec 1;13(9):2027-36. [Content Brief]
