1180676-33-8
1180676-33-8
Chemical Structure
PS47
- CAS No.: 1180676-33-8
- Formula:C17H15ClO2
- Molecular Weight:286.75
IUPAC Name: (E)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid
InChIKey: LLJYFDRQFPQGNY-NTCAYCPXSA-N
SMILES: O=C(O)/C=C(C1=CC=CC=C1)\CCC2=CC=C(Cl)C=C2
Biological Activity: PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PS47 | 99.13% | PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48. | ||||||||||||||||||||
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References
- [1]. Hindie V, et, al. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5(10):758-64. [Content Brief]
- [2]. Pastor-Flores D, et, al. PIF-pocket as a target for C. albicans Pkh selective inhibitors. ACS Chem Biol. 2013 Oct 18;8(10):2283-92. [Content Brief]
