118292-36-7
Chemical Structure
Pyrindamycin A
- CAS No.: 118292-36-7
- Formula:C26H26ClN3O8
- Molecular Weight:543.95
IUPAC Name: methyl (2R,8S)-8-(chloromethyl)-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-1,2,3,6,7,8-hexahydropyrrolo[3,2-e]indole-2-carboxylate
InChIKey: BOGFADYROAVVTF-MZHQLVBMSA-N
SMILES: O=C([C@@](NC1=C(O)C=C2N(C(C(N3)=CC4=C3C(OC)=C(OC)C(OC)=C4)=O)C[C@@H](CCl)C2=C15)(C)C5=O)OC
Biological Activity: Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml[1].
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Pyrindamycin A | Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml. | |||||||||||||||||||||
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