118499-11-9
118499-11-9
Chemical Structure
AH057
- CAS No.: 118499-11-9
- Formula:C17H22N2O
- Molecular Weight:270.37
InChIKey: WUPPLXLZQARPFF-FBMGVBCBSA-N
SMILES: OCC(CC)/N=C1C2=C(CCC/1)C3=C(C=CC(C)=C3)N2
Biological Activity: AH057 is an orally active JAK1 and JAK2 inhibitor. AH057 blocks IL-6-, IFN-α- and IFN-γ-induced JAK/STAT signaling, reduces cancer cell proliferation, invasion and colony formation, and induces apoptosis and G1 cell-cycle arrest. AH057 can be used for cervical cancer research[1].
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AH057 | AH057 is an orally active JAK1 and JAK2 inhibitor. AH057 blocks IL-6-, IFN-α- and IFN-γ-induced JAK/STAT signaling, reduces cancer cell proliferation, invasion and colony formation, and induces apoptosis and G1 cell-cycle arrest. AH057 can be used for cervical cancer research. | |||||||||||||||||||||
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