118506-26-6
118506-26-6
Chemical Structure
Myelin Basic Protein(87-99)
- CAS No.: 118506-26-6
- Formula:C74H114N20O17
- Molecular Weight:1555.82
SMILES: F[VH](F)([K])([V](P([3H])[R][P])[3H])=NI
Biological Activity: Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS)[1][2].
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Myelin Basic Protein(87-99) | Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS). | |||||||||||||||||||||
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References
- [1]. R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12. [Content Brief]
- [2]. George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J Med Chem. 2008 Dec 25;51(24):7834-42. [Content Brief]
