1187187-10-5
1187187-10-5
Chemical Structure
AN3199
- CAS No.: 1187187-10-5
- Formula:C17H18BNO5
- Molecular Weight:327.14
IUPAC Name: butyl 6-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)nicotinate
InChIKey: BJXLLSAUQIAPDB-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(OC2=CC=C(B(O)OC3)C3=C2)N=C1)OCCCC
Biological Activity: AN3199 is a PDE4 inhibitor with an IC50 of 94.5 nM. AN3199 can be used for the research of inflammation-associated diseases such as asthma and chronic obstructive pulmonary disease (COPD)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AN3199 | 99.76% | AN3199 is a PDE4 inhibitor with an IC50 of 94.5 nM. AN3199 can be used for the research of inflammation-associated diseases such as asthma and chronic obstructive pulmonary disease (COPD). | ||||||||||||||||||||
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References
- [1]. Zhang YK, et al. Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2270-4. [Content Brief]
- [2]. Akama Tsutomu, et al. Preparation of boron-containing small molecules as anti-inflammatory agents. From PCT Int. Appl. (2009), WO 2009111676 A2 20090911.
