1188407-46-6
Chemical Structure
Emtricitabine triphosphate tetrasodium salt
Synonym(s): (-)-Emtricitabine triphosphate tetrasodium salt
- CAS No.: 1188407-46-6
- Formula:C8H9FN3Na4O12P3S
- Molecular Weight:575.11
IUPAC Name: sodium ((2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl triphosphate
InChIKey: UVCVKFWKKXBGTF-YPNYOHIOSA-J
SMILES: O=P(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])OC[C@@H]1O[C@H](N2C=C(F)C(N)=NC2=O)CS1
Biological Activity: Emtricitabine triphosphate tetrasodium salt ((-)-Emtricitabine triphosphate tetrasodium salt) is the phosphorylated active metabolite of Emtricitabine (HY-17427). Emtricitabine triphosphate inhibits HIV-1 reverse transcriptase and incorporates into the nascent viral DNA chain, causing chain termination. Emtricitabine triphosphate tetrasodium salt can serve as a biomarker for assessing adherence to antiretroviral therapy. Emtricitabine triphosphate (tetrasodium salt) can be used in research related to HIV infection[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Emtricitabine triphosphate tetrasodium salt | 99.20% | Emtricitabine triphosphate tetrasodium salt ((-)-Emtricitabine triphosphate tetrasodium salt) is the phosphorylated active metabolite of Emtricitabine (HY-17427). Emtricitabine triphosphate inhibits HIV-1 reverse transcriptase and incorporates into the nascent viral DNA chain, causing chain termination. Emtricitabine triphosphate tetrasodium salt can serve as a biomarker for assessing adherence to antiretroviral therapy. Emtricitabine triphosphate (tetrasodium salt) can be used in research related to HIV infection. | ||||||||||||||||||||
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