119141-89-8
119141-89-8
Chemical Structure
(R)-Esomeprazole
Synonym(s): (R)-Omeprazole;(+)-Omeprazole
- CAS No.: 119141-89-8
- Formula:C17H19N3O3S
- Molecular Weight:345.42
IUPAC Name: (R)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
InChIKey: SUBDBMMJDZJVOS-XMMPIXPASA-N
SMILES: O=[S@@](C1=NC2=CC(OC)=CC=C2N1)CC3=NC=C(C)C(OC)=C3C
Biological Activity: (R)-Esomeprazole ((R)-Omeprazole; (+)-Omeprazole) is an orally active cytochrome P450 2C19, CYP3A4, and CYP2C9-related metabolic modulator. (R)-Esomeprazole can be used in studies of digestive system diseases and compound metabolic interactions[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R)-Esomeprazole | 96.41% | (R)-Esomeprazole ((R)-Omeprazole; (+)-Omeprazole) is an orally active cytochrome P450 2C19, CYP3A4, and CYP2C9-related metabolic modulator. (R)-Esomeprazole can be used in studies of digestive system diseases and compound metabolic interactions. | ||||||||||||||||||||
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References
- [1]. Pippa LF, et al. Impact of obesity and roux-en-Y gastric bypass on the pharmacokinetics of (R)- and (S)-omeprazole and intragastric pH. CPT Pharmacometrics Syst Pharmacol. 2024 Sep;13(9):1528-1541. [Content Brief]
- [2]. Niwa T, et al. Stereoselectivity of human cytochrome p450 in metabolic and inhibitory activities. Curr Drug Metab. 2011 Jul;12(6):549-69. [Content Brief]
