1194374-05-4
1194374-05-4
Chemical Structure
Edivoxetine hydrochloride
Synonym(s): LY 2216684 hydrochloride
- CAS No.: 1194374-05-4
- Formula:C18H27ClFNO4
- Molecular Weight:375.86
IUPAC Name: (R)-2-(5-fluoro-2-methoxyphenyl)-1-((S)-morpholin-2-yl)-1-(tetrahydro-2H-pyran-4-yl)ethan-1-ol hydrochloride
InChIKey: WJDKGRLMNSHPON-CJRXIRLBSA-N
SMILES: COC(C=CC(F)=C1)=C1C[C@@](C2CCOCC2)([C@]3([H])CNCCO3)O.Cl
Biological Activity: Edivoxetine (LY 2216684) hydrochloride is a potent and selective norepinephrine reuptake inhibitor. Edivoxetine hydrochloride can be used for the study of major depressive disorder (MDD) and attention-deficit/hyperactivity disorder (ADHD)[1][2].
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Edivoxetine hydrochloride | 99.85% | Edivoxetine (LY 2216684) hydrochloride is a potent and selective norepinephrine reuptake inhibitor. Edivoxetine hydrochloride can be used for the study of major depressive disorder (MDD) and attention-deficit/hyperactivity disorder (ADHD). | ||||||||||||||||||||
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References
- [1]. Jin L,et al. Clinical outcomes from an opeJin L, Xu W, Krefetz D, et al. Clinical outcomes from an open-label study of edivoxetine use in pediatric patients with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2013;23(3):200-207 [Content Brief]
- [2]. Kielbasa W, et al. The effect of hepatic or renal impairment on the pharmacokinetics of edivoxetine, a selective norepinephrine transporter reuptake inhibitor. Eur J Clin Pharmacol. 2013;69(12):2011-2019. [Content Brief]
