119478-55-6
Chemical Structure
Danofloxacin mesylate
Synonym(s): CP 76136-27
- CAS No.: 119478-55-6
- Formula:C20H24FN3O6S
- Molecular Weight:453.48
IUPAC Name: 1-cyclopropyl-6-fluoro-7-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compound with methanesulfonic acid (1:1)
InChIKey: APFDJSVKQNSTKF-FXMYHANSSA-N
SMILES: O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4[C@](C5)([H])CN(C)[C@]5([H])C4)=C3)C1=O)O.CS(=O)(O)=O
Biological Activity: Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. Danofloxacin mesylate has a broad spectrum of bactericidal activity, mainly inhibiting the DNA cycloenzyme of the bacteria. In addition, Danofloxacin mesylate is a substrate for ATP-dependent efflux transporters (P-gp and MRP2)[1][2][3].
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Danofloxacin mesylate | 99.88% | Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. Danofloxacin mesylate has a broad spectrum of bactericidal activity, mainly inhibiting the DNA cycloenzyme of the bacteria. In addition, Danofloxacin mesylate is a substrate for ATP-dependent efflux transporters (P-gp and MRP2). | ||||||||||||||||||||
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Danofloxacin mesylate (Standard) | ≥98% | Danofloxacin mesylate (Standard) is the analytical standard of Danofloxacin mesylate. This product is intended for research and analytical applications. Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. Danofloxacin mesylate has a broad spectrum of bactericidal activity, mainly inhibiting the DNA cycloenzyme of the bacteria. In addition, Danofloxacin mesylate is a substrate for ATP-dependent efflux transporters (P-gp and MRP2). | ||||||||||||||||||||
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Danofloxacin-d3 mesylate | Danofloxacin-d3 (mesylate) is the deuterium labeled Danofloxacin mesylate. Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone antibacterial for veterinary use. | |||||||||||||||||||||
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References
- [1]. Schrickx JA, et al. Danofloxacin-mesylate is a substrate for ATP-dependent efflux transporters. Br J Pharmacol. 2007 Feb;150(4):463-9. [Content Brief]
- [2]. Giles, C.J., et al., Clinical pharmacokinetics of parenterally administered danofloxacin in cattle. J Vet Pharmacol Ther, 1991. 14(4): p. 400-10. [Content Brief]
- [3]. Sartini I, et al. Danofloxacin pharmacokinetics and tissue residues in Bilgorajska geese. Res Vet Sci. 2021 May;136:11-17. [Content Brief]
