1195030-24-0
1195030-24-0
Chemical Structure
2'-O-Methyladenosine-d3
- CAS No.: 1195030-24-0
- Formula:C11H12D3N5O4
- Molecular Weight:284.29
IUPAC Name: (2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(methoxy-d3)tetrahydrofuran-3-ol
InChIKey: FPUGCISOLXNPPC-YZLHILBGSA-N
SMILES: O[C@H]1[C@@H](OC([2H])([2H])[2H])[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1CO
Biological Activity: 2'-O-Methyl Adenosine-d3 is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities [1][2].
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2'-O-Methyladenosine-d3 | 97.54% | 2'-O-Methyl Adenosine-d3 is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities . | ||||||||||||||||||||
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References
- [1]. Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9. [Content Brief]
- [2]. Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8. [Content Brief]
