119625-78-4
119625-78-4
Chemical Structure
Terlakiren
Synonym(s): CP-80,794
- CAS No.: 119625-78-4
- Formula:C31H48N4O7S
- Molecular Weight:620.80
IUPAC Name: isopropyl (2R,3S)-4-cyclohexyl-2-hydroxy-3-((R)-3-(methylthio)-2-((S)-2-(morpholine-4-carboxamido)-3-phenylpropanamido)propanamido)butanoate
InChIKey: UZQBKCWYZBHBOW-YIPNQBBMSA-N
SMILES: CC(C)OC([C@H](O)[C@@](CC1CCCCC1)([H])NC([C@H](CSC)NC([C@@H](NC(N2CCOCC2)=O)CC3=CC=CC=C3)=O)=O)=O
Biological Activity: Terlakiren (CP-80,794) is an orally active inhibitor of renin. Terlakiren inhibits the efficacy of human renin with an IC50 value of 0.7 nM. Terlakiren has potential applications in hypertension[1].
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Terlakiren | Terlakiren (CP-80,794) is an orally active inhibitor of renin. Terlakiren inhibits the efficacy of human renin with an IC50 value of 0.7 nM. Terlakiren has potential applications in hypertension. | |||||||||||||||||||||
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