1196504-54-7
1196504-54-7
Chemical Structure
GDC0575 hydrochloride
Synonym(s): ARRY-575 hydrochloride; RG7741 hydrochloride
- CAS No.: 1196504-54-7
- Formula:C16H21BrClN5O
- Molecular Weight:414.73
IUPAC Name: (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide hydrochloride
InChIKey: GKZACMRNGHGLEJ-HNCPQSOCSA-N
SMILES: O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32.Cl
Biological Activity: GDC0575 (ARRY-575) hydrochloride is a highly-selective and orally active Chk1 (IC50=1.2 nM) inhibitor. GDC0575 (ARRY-575) hydrochloride can be used for colitis-associated cancer (CAC) and colitis research[1].
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GDC0575 hydrochloride | GDC0575 (ARRY-575) hydrochloride is a highly-selective and orally active Chk1 (IC50=1.2 nM) inhibitor. GDC0575 (ARRY-575) hydrochloride can be used for colitis-associated cancer (CAC) and colitis research. | |||||||||||||||||||||
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