1197194-61-8
1197194-61-8
Chemical Structure
Endoxifen E-isomer hydrochloride
Synonym(s): E-Endoxifen hydrochloride
- CAS No.: 1197194-61-8
- Formula:C25H28ClNO2
- Molecular Weight:409.95
IUPAC Name: (E)-4-(1-(4-(2-(methylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol hydrochloride
InChIKey: RPFIMPDXTABYCN-QREUMGABSA-N
SMILES: OC1=CC=C(/C(C2=CC=C(OCCNC)C=C2)=C(C3=CC=CC=C3)/CC)C=C1.[H]Cl
Biological Activity: Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride), an E-isomer of Endoxifen, is an impurity in Endoxifen Z-isomer agent substance. Endoxifen E-isomer hydrochloride exhibits antiestrogenic effects[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Endoxifen E-isomer hydrochloride | 98.20% | Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride), an E-isomer of Endoxifen, is an impurity in Endoxifen Z-isomer agent substance. Endoxifen E-isomer hydrochloride exhibits antiestrogenic effects. | ||||||||||||||||||||
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References
- [1]. Elkins P, et, al. Characterization of the isomeric configuration and impurities of (Z)-endoxifen by 2D NMR, high resolution LC⬜MS, and quantitative HPLC analysis. J Pharm Biomed Anal. 2014 Jan;88:174-9. [Content Brief]
- [2]. Zheng Y, et, al. Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. Drug Metab Dispos. 2007 Oct;35(10):1942-8. [Content Brief]
