1197996-80-7
1197996-80-7
Chemical Structure
CBL0137
Synonym(s): Curaxin 137; CBL-C137
- CAS No.: 1197996-80-7
- Formula:C21H24N2O2
- Molecular Weight:336.43
IUPAC Name: 1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)
InChIKey: JKCSODVERGVDLT-UHFFFAOYSA-N
SMILES: CC(NCCN1C2=C(C3=C1C=CC(C(C)=O)=C3)C=C(C(C)=O)C=C2)C
Biological Activity: CBL0137, a curaxin compound, is a histone chaperone facilitates chromatin transcription (FACT) inhibitor. CBL0137 downregulates NF-κB and activates p53. CBL0137 restores both histone H3 acetylation and trimethylation. CBL0137 is an anticancer agent. CBL0137 induces cancer cell apoptosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CBL0137 | 99.73% | CBL0137, a curaxin compound, is a histone chaperone facilitates chromatin transcription (FACT) inhibitor. CBL0137 downregulates NF-κB and activates p53. CBL0137 restores both histone H3 acetylation and trimethylation. CBL0137 is an anticancer agent. CBL0137 induces cancer cell apoptosis. | ||||||||||||||||||||
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