1206163-45-2
1206163-45-2
Chemical Structure
Solcitinib
Synonym(s): GSK-2586184; GLPG-0778
- CAS No.: 1206163-45-2
- Formula:C22H23N5O2
- Molecular Weight:389.45
IUPAC Name: N-(5-(4-(3,3-dimethylazetidine-1-carbonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide
InChIKey: MPYACSQFXVMWNO-UHFFFAOYSA-N
SMILES: O=C(C1CC1)NC2=NN3C(C4=CC=C(C(N5CC(C)(C)C5)=O)C=C4)=CC=CC3=N2
Biological Activity: Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively; Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Solcitinib | 99.51% | Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively; Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis. | ||||||||||||||||||||
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