120639-92-1
Chemical Structure
13-Dilignoceroyl glycerol
Synonym(s): 1,3-Ditetracosanoin
- CAS No.: 120639-92-1
- Formula:C51H100O5
- Molecular Weight:793.34
IUPAC Name: 2-hydroxypropane-1,3-diyl ditetracosanoate
InChIKey: FVVAKYSCTIVMFI-UHFFFAOYSA-N
SMILES: O=C(CCCCCCCCCCCCCCCCCCCCCCC)OCC(COC(CCCCCCCCCCCCCCCCCCCCCCC)=O)O
Biological Activity: 13-Dilignoceroyl glycerol is a diacylglycerol containing lignoceric acid (HY-121883 ) at the sn-1 and sn-3 positions. Lignoceric acid is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy research[1][2].
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13-Dilignoceroyl glycerol | 13-Dilignoceroyl glycerol is a diacylglycerol containing lignoceric acid (HY-121883 ) at the sn-1 and sn-3 positions. Lignoceric acid is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy research. | |||||||||||||||||||||
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References
- [1]. Petroni A, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234(10):18344-18348. [Content Brief]
- [2]. Bourre JM, et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy). Eur J Biochem. 1977 Jan 3;72(1):41-7. [Content Brief]
