1213269-23-8
1213269-23-8
Chemical Structure
WZ4002
- CAS No.: 1213269-23-8
- Formula:C25H27ClN6O3
- Molecular Weight:494.97
IUPAC Name: N-(3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)acrylamide
InChIKey: ITTRLTNMFYIYPA-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(N2CCN(CC2)C)=C1)NC3=NC=C(C(OC4=CC(NC(C=C)=O)=CC=C4)=N3)Cl
Biological Activity: WZ4002 is a mutant selective EGFR inhibitor with IC50s of 2, 8, 3 and 2 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750 and EGFRE746_A750/T790M, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WZ4002 | 98.99% | WZ4002 is a mutant selective EGFR inhibitor with IC50s of 2, 8, 3 and 2 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750 and EGFRE746_A750/T790M, respectively. | ||||||||||||||||||||
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