1214265-56-1
1214265-56-1
Chemical Structure
WZ-3146
- CAS No.: 1214265-56-1
- Formula:C24H25ClN6O2
- Molecular Weight:464.95
IUPAC Name: N-(3-((5-chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)acrylamide
InChIKey: APHGZZPEOCCYNO-UHFFFAOYSA-N
SMILES: CN1CCN(C2=CC=C(C=C2)NC3=NC=C(C(OC4=CC(NC(C=C)=O)=CC=C4)=N3)Cl)CC1
Biological Activity: WZ3146 is a mutant selective EGFR inhibitor with IC50s of 2, 2, 5, 14 and 66 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750, EGFRE746_A750/T790M and EGFR, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WZ-3146 | 99.28% | WZ3146 is a mutant selective EGFR inhibitor with IC50s of 2, 2, 5, 14 and 66 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750, EGFRE746_A750/T790M and EGFR, respectively. | ||||||||||||||||||||
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