1215622-76-6
Chemical Structure
3-Hydroxyoctanoic acid-d12
- CAS No.: 1215622-76-6
- Formula:C8H4D12O3
- Molecular Weight:172.28
IUPAC Name: 3-hydroxyoctanoic-3,4,4,5,5,6,6,7,7,8,8,8-d12 acid
InChIKey: NDPLAKGOSZHTPH-SDFLALOFSA-N
SMILES: [2H]C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C(CC(O)=O)(O)[2H])[2H])[2H])[2H])[2H])[2H]
Biological Activity: 3-Hydroxyoctanoic acid-d12 is the deuterated-labeled 3-Hydroxyoctanoic acid (HY-113058). 3-Hydroxyoctanoic acid is a medium-chain β-hydroxy fatty acid that possesses antibacterial, antifungal, and quorum-sensing regulatory activities. 3-Hydroxyoctanoic acid is an endogenous agonist of the human HCAR3 receptor, decreases intracellular cAMP, reduces IL-1beta secretion, increases IL-10 secretion, and decreases ROS production in macrophages. 3-Hydroxyoctanoic acid inhibits quorum-sensing-regulated pyocyanin production in Pseudomonas aeruginosa PAO1 and inhibits the yeast-to-hypha transition in Candida albicans. 3-Hydroxyoctanoic acid is used in research related to metabolism, bacterial infections, and fungal infections[1][2][3].
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3-Hydroxyoctanoic acid-d12 | 3-Hydroxyoctanoic acid-d12 is the deuterated-labeled 3-Hydroxyoctanoic acid (HY-113058). 3-Hydroxyoctanoic acid is a medium-chain β-hydroxy fatty acid that possesses antibacterial, antifungal, and quorum-sensing regulatory activities. 3-Hydroxyoctanoic acid is an endogenous agonist of the human HCAR3 receptor, decreases intracellular cAMP, reduces IL-1beta secretion, increases IL-10 secretion, and decreases ROS production in macrophages. 3-Hydroxyoctanoic acid inhibits quorum-sensing-regulated pyocyanin production in Pseudomonas aeruginosa PAO1 and inhibits the yeast-to-hypha transition in Candida albicans. 3-Hydroxyoctanoic acid is used in research related to metabolism, bacterial infections, and fungal infections. | |||||||||||||||||||||
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3-Hydroxyoctanoic acid (Standard) | ≥98% | 3-Hydroxyoctanoic acid (Standard) is the analytical standard of 3-Hydroxyoctanoic acid (HY-113058). This product is intended for research and analytical applications. 3-Hydroxyoctanoic acid is a medium-chain β-hydroxy fatty acid that possesses antibacterial, antifungal, and quorum-sensing regulatory activities. 3-Hydroxyoctanoic acid is an endogenous agonist of the human HCAR3 receptor, decreases intracellular cAMP, reduces IL-1beta secretion, increases IL-10 secretion, and decreases ROS production in macrophages. 3-Hydroxyoctanoic acid inhibits quorum-sensing-regulated pyocyanin production in Pseudomonas aeruginosa PAO1 and inhibits the yeast-to-hypha transition in Candida albicans. 3-Hydroxyoctanoic acid is used in research related to metabolism, bacterial infections, and fungal infections. | ||||||||||||||||||||
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3-Hydroxyoctanoic acid | 98.0% | 3-Hydroxyoctanoic acid is a medium-chain β-hydroxy fatty acid that possesses antibacterial, antifungal, and quorum-sensing regulatory activities. 3-Hydroxyoctanoic acid is an endogenous agonist of the human HCAR3 receptor, decreases intracellular cAMP, reduces IL-1beta secretion, increases IL-10 secretion, and decreases ROS production in macrophages. 3-Hydroxyoctanoic acid inhibits quorum-sensing-regulated pyocyanin production in Pseudomonas aeruginosa PAO1 and inhibits the yeast-to-hypha transition in Candida albicans. 3-Hydroxyoctanoic acid is used in research related to metabolism, bacterial infections, and fungal infections. | ||||||||||||||||||||
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References
- [1]. Peters A, et al. Hydroxycarboxylic acid receptor 3 and GPR84 - Two metabolite-sensing G protein-coupled receptors with opposing functions in innate immune cells. Pharmacological research. 2022 Feb;176:106047.
- [2]. Kapolka NJ, et al. HCAR3: an underexplored metabolite sensor. Nat Rev Drug Discov. 2020 Oct;19(11):745.
- [3]. Radivojevic J, et al. Polyhydroxyalkanoate-based 3-hydroxyoctanoic acid and its derivatives as a platform of bioactive compounds. Applied microbiology and biotechnology. 2016 Jan;100(1):161-72.
