121617-11-6
Chemical Structure
Saviprazole
Synonym(s): HOE-731
- CAS No.: 121617-11-6
- Formula:C15H10F7N3O2S2
- Molecular Weight:461.38
IUPAC Name: 2-(((4-(2,2,3,3,4,4,4-heptafluorobutoxy)pyridin-2-yl)methyl)sulfinyl)-1H-thieno[3,4-d]imidazole
InChIKey: ARFGGIRJBPTBPP-UHFFFAOYSA-N
SMILES: O=S(CC1=NC=CC(OCC(F)(C(F)(C(F)(F)F)F)F)=C1)C2=NC3=CSC=C3N2
Biological Activity: Saviprazole (HOE-731) is a H+,K+-ATPase inhibitor. Saviprazole inhibits gastric acid secretion. Saviprazole inhibits histamine- and dbcAMP-stimulated [14C]aminopyrine uptake, dbcAMP-induced oxygen consumption. Saviprazole can be used in research related to gastrointestinal diseases, such as gastric ulcers and acid reflux[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Saviprazole | 96.05% | Saviprazole (HOE-731) is a H+,K+-ATPase inhibitor. Saviprazole inhibits gastric acid secretion. Saviprazole inhibits histamine- and dbcAMP-stimulated [14C]aminopyrine uptake, dbcAMP-induced oxygen consumption. Saviprazole can be used in research related to gastrointestinal diseases, such as gastric ulcers and acid reflux. | ||||||||||||||||||||
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References
- [1]. Herling AW, et al. The inhibitory effect of HOE 731 in isolated rabbit gastric glands. Biochem Pharmacol. 1990;40(8):1809-1814. [Content Brief]
- [2]. Herling AW, et al. Gastric acid inhibitory profile of saviprazole (HOE 731) compared to omeprazole. Pharmacology. 1991;43(6):293-303. [Content Brief]
