1216398-09-2
1216398-09-2
Chemical Structure
YM-298198 hydrochloride
- CAS No.: 1216398-09-2
- Formula:C18H23ClN4OS
- Molecular Weight:378.92
IUPAC Name: 6-amino-N-cyclohexyl-N,3-dimethylbenzo[4,5]imidazo[2,1-b]thiazole-2-carboxamide hydrochloride
InChIKey: WYTJVUVCSUWZTH-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)N2C3=CC(N)=CC=C3N=C2S1)N(C4CCCCC4)C.[H]Cl
Biological Activity: YM-298198 hydrochloride is a high-affinity, selective, orally active, and non-competitive antagonist of metabotropic glutamate receptor type 1 (mGluR1). YM-298198 hydrochloride can be used for the research of neurological disorders[1].
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YM-298198 hydrochloride | 98.01% | YM-298198 hydrochloride is a high-affinity, selective, orally active, and non-competitive antagonist of metabotropic glutamate receptor type 1 (mGluR1). YM-298198 hydrochloride can be used for the research of neurological disorders. | ||||||||||||||||||||
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References
- [1]. Kohara, A, et al. Radioligand Binding Properties and Pharmacological Characterization of 6-Amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a High-Affinity, Selective, and Noncompetitive Antagonist of Metabotropic Glutamate Receptor Type 1. J Pharmacol Exp Ther. 2005 Oct;315(1):163-9. [Content Brief]
