121748-12-7
Chemical Structure
Leonuriside A
- CAS No.: 121748-12-7
- Formula:C14H20O9
- Molecular Weight:332.30
IUPAC Name: (2S,3R,4S,5S,6R)-2-(4-hydroxy-2,6-dimethoxyphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: NOQYJICHFNSIFZ-DIACKHNESA-N
SMILES: O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=C(OC)C=C(O)C=C2OC
Biological Activity: Leonuriside A is a phenolic compound that can be isolated from Leonurus japonicus. Leonuriside A exhibits anti-inflammatory activity, which inhibits the iNOS-related inflammatory pathway in LPS (HY-D1056)-stimulated macrophages, thereby suppressing the production of nitric oxide (NO) with an IC50 of 15.6 μM. Leonuriside A can be used in studies of anti-inflammatory natural products and the molecular mechanisms of inflammation[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Leonuriside A | 99.79% | Leonuriside A is a phenolic compound that can be isolated from Leonurus japonicus. Leonuriside A exhibits anti-inflammatory activity, which inhibits the iNOS-related inflammatory pathway in LPS (HY-D1056)-stimulated macrophages, thereby suppressing the production of nitric oxide (NO) with an IC50 of 15.6 μM. Leonuriside A can be used in studies of anti-inflammatory natural products and the molecular mechanisms of inflammation. | ||||||||||||||||||||
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References
- [1]. Ba Vinh L, et al. Bioactive triterpene glycosides from the fruit of Stauntonia hexaphylla and insights into the molecular mechanism of its inflammatory effects. Bioorganic & medicinal chemistry letters. 2019 Aug 15;29(16):2085-2089. [Content Brief]
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[2]. Dang Hau Viet, et al. A New Megastigmane Glucoside and Other Constituents from Desmodium gangeticum, Journal of Chemistry, 2020, 7416973.
- [3]. Minh TT. et al. Lignans from the stems of Clerodendrum inerme Gaertn. VJCH, 59: 187-191.
