121768-39-6
Chemical Structure
4-Pyridylmethyl adamantanecarboxamide
- CAS No.: 121768-39-6
- Formula:C17H22N2O
- Molecular Weight:270.37
IUPAC Name: (4-chlorophenyl)(3,4-dihydroisoquinolin-2(1H)-yl)methanone
InChIKey: GYWQBPYNAGLBSC-MSNLLQCJSA-N
SMILES: O=C(NCC1=CC=NC=C1)C2(C3)C[C@H](C4)C[C@@H]3C[C@H]4C2
Biological Activity: 4-Pyridylmethyl adamantanecarboxamide (Compound 11) is an Aromatase inhibitor with an IC50 of 1.5 μM against hAromatase. 4-Pyridylmethyl adamantanecarboxamide inhibits the C17,20-lyase activity of testicular cytochrome P45017α with an IC50 of 1600 nM, and also inhibits the 17α-hydroxylase activity of this enzyme with an IC50 of 7700 nM. 4-Pyridylmethyl adamantanecarboxamide can be used in the research of prostate cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Pyridylmethyl adamantanecarboxamide | 99.83% | 4-Pyridylmethyl adamantanecarboxamide (Compound 11) is an Aromatase inhibitor with an IC50 of 1.5 μM against hAromatase. 4-Pyridylmethyl adamantanecarboxamide inhibits the C17,20-lyase activity of testicular cytochrome P45017α with an IC50 of 1600 nM, and also inhibits the 17α-hydroxylase activity of this enzyme with an IC50 of 7700 nM. 4-Pyridylmethyl adamantanecarboxamide can be used in the research of prostate cancer. | ||||||||||||||||||||
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