121817-37-6
Chemical Structure
Lansiumamide B
- CAS No.: 121817-37-6
- Formula:C18H17NO
- Molecular Weight:263.33
InChIKey: VJGRWRRIAJQNFU-NQDQBVNISA-N
SMILES: CN(/C=C\C1=CC=CC=C1)C(/C=C/C2=CC=CC=C2)=O
Biological Activity: Lansiumamide B is a cinnamamide alkaloid, Antifungal agent and Insecticide. Lansiumamide B is isolated from the seeds of Clausena lansium. Lansiumamide B inhibits the phosphorylation of p38 MAPK, and decreases the protein and mRNA levels of TNF-α. Lansiumamide B induces abnormal mycelial growth, cell content leakage and cell wall degradation in Rhizoctonia solani. Lansiumamide B causes the death of early 4th-instar larvae of Aedes albopictus. Lansiumamide B exhibits anticonvulsant effects in epileptic rat models. Lansiumamide B can be used in studies related to plant fungal diseases[1][2][3][4].
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Lansiumamide B | Lansiumamide B is a cinnamamide alkaloid, Antifungal agent and Insecticide. Lansiumamide B is isolated from the seeds of Clausena lansium. Lansiumamide B inhibits the phosphorylation of p38 MAPK, and decreases the protein and mRNA levels of TNF-α. Lansiumamide B induces abnormal mycelial growth, cell content leakage and cell wall degradation in Rhizoctonia solani. Lansiumamide B causes the death of early 4th-instar larvae of Aedes albopictus. Lansiumamide B exhibits anticonvulsant effects in epileptic rat models. Lansiumamide B can be used in studies related to plant fungal diseases. | |||||||||||||||||||||
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References
- [1]. Jia Y, et al. Lansiumamide B induced the degradation of polysaccharides and oligosaccharides showing antifungal activity against Rhizoctonia solani[J]. Industrial Crops and Products, 2024, 214: 118529.
- [2]. Matsui T, et al. Lansiumamide B and SB-204900 isolated from Clausena lansium inhibit histamine and TNF-α release from RBL-2H3 cells. Inflamm Res. 2013 Mar;62(3):333-41. [Content Brief]
- [3]. Xu H, et al. Synthesis and Fungicidal Activity of Lansiumamide A and B and Their Derivatives. Molecules (Basel, Switzerland). 2018 Jun 21;23(7):1499. [Content Brief]
- [4]. Han Y, et al. Larvicidal activity of lansiumamide B from the seeds of Clausena lansium against Aedes albopictus (Diptera: Culicidae). Parasitology research. 2013 Feb;112(2):511-6. [Content Brief]
