121912-19-4
121912-19-4
Chemical Structure
Achatin I
- CAS No.: 121912-19-4
- Formula:C18H24N4O7
- Molecular Weight:408.41
IUPAC Name: glycyl-D-phenylalanyl-L-alanyl-L-aspartic acid
InChIKey: ZCPBEAHAVUJKAE-UHTWSYAYSA-N
SMILES: O=C(O)C[C@@H](C(O)=O)NC([C@H](C)NC([C@@H](CC1=CC=CC=C1)NC(CN)=O)=O)=O
Biological Activity: Achatin I is a neuroexcitatory tetrapeptide. Achatin I can be derived from Achatina fulica férussac. Achatin-I induces a voltage-dependent inward current. Achatin-I shows marked excitatory effects on the three Achatina giant neurones, PON, TAN and V-RCDN[1][2].
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Achatin I | Achatin I is a neuroexcitatory tetrapeptide. Achatin I can be derived from Achatina fulica férussac. Achatin-I induces a voltage-dependent inward current. Achatin-I shows marked excitatory effects on the three Achatina giant neurones, PON, TAN and V-RCDN. | |||||||||||||||||||||
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References
- [1]. Kamatani Y, et al. Achatin-I, an endogenous neuroexcitatory tetrapeptide from Achatina fulica Férussac containing a D-amino acid residue. Biochem Biophys Res Commun. 1989 May 15;160(3):1015-20. [Content Brief]
- [2]. Kamatani Y, et al. Isolation of achatin-I, a neuroactive tetrapeptide having a D-phenylalanine residue, from Achatina ganglia, and its effects on Achatina giant neurones. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1991;98(1):97-103. [Content Brief]
