1220515-87-6
1220515-87-6
Chemical Structure
3'-ONH2-dATP
- CAS No.: 1220515-87-6
- Formula:C10H17N6O12P3
- Molecular Weight:506.20
InChIKey: JRWRMKPKCJGCKT-RRKCRQDMSA-N
SMILES: O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C=NC3=C2N=CN=C3N)C[C@@H]1ON)(O)=O)(O)=O
Biological Activity: 3'-ONH2-dATP is a 3'-O-blocked reversible terminator deoxynucleotide triphosphate. 3'-ONH2-dATP stops DNA polymerization after single-nucleotide addition to an initiator strand, and its 3'-ONH2 blocking group can be removed to restore a free 3'-OH for subsequent extension[1].
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3'-ONH2-dATP | 3'-ONH2-dATP is a 3'-O-blocked reversible terminator deoxynucleotide triphosphate. 3'-ONH2-dATP stops DNA polymerization after single-nucleotide addition to an initiator strand, and its 3'-ONH2 blocking group can be removed to restore a free 3'-OH for subsequent extension. | |||||||||||||||||||||
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