122207-62-9
122207-62-9
Chemical Structure
Ac-RGDS-NH2
- CAS No.: 122207-62-9
- Formula:C17H30N8O8
- Molecular Weight:474.47
InChIKey: GFOJSWCCTWFSJD-DCAQKATOSA-N
SMILES: NC([C@H](CO)NC([C@H](CC(O)=O)NC(CNC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)=O)=O
Biological Activity: Ac-RGDS-NH2, a tetrapeptide, is an integrin antagonist. Ac-RGDS-NH2 competitively binds to the GPIIb/IIIa receptor (Ki = 4.2 μM), inhibiting the binding of fibrinogen to platelets and thereby effectively suppressing platelet aggregation. Ac-RGDS-NH2 can be used for research on thrombosis[1].
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Ac-RGDS-NH2 | Ac-RGDS-NH2, a tetrapeptide, is an integrin antagonist. Ac-RGDS-NH2 competitively binds to the GPIIb/IIIa receptor (Ki = 4.2 μM), inhibiting the binding of fibrinogen to platelets and thereby effectively suppressing platelet aggregation. Ac-RGDS-NH2 can be used for research on thrombosis. | |||||||||||||||||||||
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