1223194-71-5
Chemical Structure
S07-2010
- CAS No.: 1223194-71-5
- Formula:C19H21N3O3S
- Molecular Weight:371.45
IUPAC Name: (2R,3R,4S,5R)-2-(6-(amino-15N)-9H-purin-9-yl-13C5-15N4)-5-(hydroxymethyl-13C)tetrahydrofuran-3,4-diol-2,3,4,5-13C4
InChIKey: WVRKQDZPZOUPNW-UHFFFAOYSA-N
SMILES: O=C1CCCC2=CC(C(CSC3=NC(CCC)=CC(N3)=O)=O)=CC=C2N1
Biological Activity: S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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S07-2010 | 98.35% | S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells. | ||||||||||||||||||||
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