122454-69-7
Chemical Structure
SKF-105809
- CAS No.: 122454-69-7
- Formula:C18H17N3OS
- Molecular Weight:323.41
IUPAC Name: 2-(4-(methylsulfinyl)phenyl)-3-(pyridin-4-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
InChIKey: KSEJZTWORQXILM-UHFFFAOYSA-N
SMILES: O=S(C)C1=CC=C(C2=C(C3=CC=NC=C3)N(CCC4)C4=N2)C=C1
Biological Activity: SKF-105809 is a dual-action inhibitor of lipoxygenase and COX. SKF-105809 inhibits edema and inflammatory cell infiltration in mouse models of ear, paw, and peritoneum inflammation. SKF-105809 inhibits the production of relevant acute-phase reactive proteins in a mouse model of arthritis. SKF-105809 exhibits analgesic activity in a mouse abdominal contraction test and inhibits ulceration. SKF-105809 can be used in research on inflammatory and immune system diseases such as peritonitis and arthritis[1].
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SKF-105809 | SKF-105809 is a dual-action inhibitor of lipoxygenase and COX. SKF-105809 inhibits edema and inflammatory cell infiltration in mouse models of ear, paw, and peritoneum inflammation. SKF-105809 inhibits the production of relevant acute-phase reactive proteins in a mouse model of arthritis. SKF-105809 exhibits analgesic activity in a mouse abdominal contraction test and inhibits ulceration. SKF-105809 can be used in research on inflammatory and immune system diseases such as peritonitis and arthritis. | |||||||||||||||||||||
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