122520-79-0
122520-79-0
Chemical Structure
Tyrphostin AG30
Synonym(s): AG30
- CAS No.: 122520-79-0
- Formula:C10H7NO4
- Molecular Weight:205.17
IUPAC Name: (E)-2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid
InChIKey: CJMWBHLWSMKFSM-XVNBXDOJSA-N
SMILES: O=C(/C(C#N)=C/C1=CC=C(C(O)=C1)O)O
Biological Activity: Tyrphostin AG30 (AG30) is a potent and selective EGFR tyrosine kinase inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Tyrphostin AG30 | 98.51% | Tyrphostin AG30 (AG30) is a potent and selective EGFR tyrosine kinase inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Volberg T, et al. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 1992 May;11(5):1733-42. [Content Brief]
- [2]. Wessely O, et al. Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 1997 May;8(5):481-93. [Content Brief]
