1227634-69-6
1227634-69-6
Chemical Structure
GNF351
- CAS No.: 1227634-69-6
- Formula:C24H25N7
- Molecular Weight:411.50
IUPAC Name: N-(2-(1H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methylpyridin-3-yl)-9H-purin-6-amine
InChIKey: ABXIUYMKZDZUDC-UHFFFAOYSA-N
SMILES: CC1=CN=CC(C2=NC(NCCC3=CNC4=C3C=CC=C4)=C5N=CN(C(C)C)C5=N2)=C1
Biological Activity: GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GNF351 | 99.87% | GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes. | ||||||||||||||||||||
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GNF351 (Standard) | ≥98% | GNF351 (Standard) is the analytical standard of GNF351 (HY-102023). This product is intended for research and analytical applications. GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes. | ||||||||||||||||||||
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