1228927-36-3
1228927-36-3
Chemical Structure
Glu-urea-Glu-NHS ester
- CAS No.: 1228927-36-3
- Formula:C27H43N3O11
- Molecular Weight:585.64
IUPAC Name: 2-(tert-butyl) 3-ethyl (1S,3S,4S,5R)-5-hydroxy-2-azabicyclo[2.2.2]octane-2,3-dicarboxylate
InChIKey: RLHXPXLWGMDVAY-IRXDYDNUSA-N
SMILES: CC(C)(C)OC(CC[C@@H](C(OC(C)(C)C)=O)NC(N[C@H](C(OC(C)(C)C)=O)CCC(ON1C(CCC1=O)=O)=O)=O)=O
Biological Activity: Glu-urea-Glu-NHS ester is an activated N-hydroxysuccinamide (NHS) ester of Glu-urea-Glu. Glu-urea-Glu-NHS ester can be used for synthesis of small-molecule prostate-specific membrane antigen (PSMA) inhibitors, imaging agents (such as PSMAi-PEG conjugates), and targeted drug delivery vehicles[1][2].
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Glu-urea-Glu-NHS ester | 99.51% | Glu-urea-Glu-NHS ester is an activated N-hydroxysuccinamide (NHS) ester of Glu-urea-Glu. Glu-urea-Glu-NHS ester can be used for synthesis of small-molecule prostate-specific membrane antigen (PSMA) inhibitors, imaging agents (such as PSMAi-PEG conjugates), and targeted drug delivery vehicles. | ||||||||||||||||||||
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References
- [1]. Lu G, et al. Synthesis and SAR of ⁹⁹mTc/Re-labeled small molecule prostate specific membrane antigen inhibitors with novel polar chelates. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1557-63. [Content Brief]
- [2]. Jung-Jae Lee. Chemiluminescent and fluorescent nanoparticle for optical imaging of cancer. WO2020081581A1. 2020-04-23.
