1229018-87-4
1229018-87-4
Chemical Structure
TPN171
- CAS No.: 1229018-87-4
- Formula:C24H35N5O3
- Molecular Weight:441.57
IUPAC Name: N-(3-(4,5-diethyl-6-oxo-1,6-dihydropyrimidin-2-yl)-4-propoxyphenyl)-2-(4-methylpiperazin-1-yl)acetamide
InChIKey: PIOIVHHIGWTEJQ-UHFFFAOYSA-N
SMILES: CCCOC1=C(C2=NC(CC)=C(CC)C(N2)=O)C=C(NC(CN3CCN(C)CC3)=O)C=C1
Biological Activity: TPN171 is a potent, selective and oral bioavailable inhibitor of phosphodiesterase type 5 (PDE5) with an IC50 of 0.62 nM, being developed for the treatment of pulmonary arterial hypertension (PAH)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
TPN171 | 98.10% | TPN171 is a potent, selective and oral bioavailable inhibitor of phosphodiesterase type 5 (PDE5) with an IC50 of 0.62 nM, being developed for the treatment of pulmonary arterial hypertension (PAH). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
