1229363-11-4
1229363-11-4
Chemical Structure
FFA2 agonist-2
- CAS No.: 1229363-11-4
- Formula:C23H20Cl2N2O3S
- Molecular Weight:475.39
InChIKey: LCRQPJWEPVZEBE-OAHLLOKOSA-N
SMILES: OC(C[C@@H](CC1=CC=CC=C1)C(N(C2CC2)C3=NC(C4=C(C=CC(Cl)=C4)Cl)=CS3)=O)=O
Biological Activity: FFA2 agonist-2 is a potent agonist of the FFA2 (GPR43) receptor, with a pEC50 of 7.9 for human FFA2, and a pEC50 of 7.3 for murine FFA2. FFA2 agonist-2 acts as an orthosteric agonist and shows no obvious cross‑activity against FFA1, FFA3 and FFA4. FFA2 agonist-2 can be used for FFA2 receptor research in type 2 diabetes and metabolic disorders[1].
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FFA2 agonist-2 | FFA2 agonist-2 is a potent agonist of the FFA2 (GPR43) receptor, with a pEC50 of 7.9 for human FFA2, and a pEC50 of 7.3 for murine FFA2. FFA2 agonist-2 acts as an orthosteric agonist and shows no obvious cross‑activity against FFA1, FFA3 and FFA4. FFA2 agonist-2 can be used for FFA2 receptor research in type 2 diabetes and metabolic disorders. | |||||||||||||||||||||
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