1229611-73-7
1229611-73-7
Chemical Structure
LCRF-0004
- CAS No.: 1229611-73-7
- Formula:C28H18F4N6O2S
- Molecular Weight:578.54
IUPAC Name: N-(3-fluoro-4-((2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
InChIKey: DVRMYRDLCLUXQP-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C(F)=C1)OC2=C3C(C=C(S3)C4=CN(C=N4)C)=NC=C2)C5=C(N(N=C5)C6=CC=CC=C6)C(F)(F)F
Biological Activity: LCRF-0004 is a potent inhibitor of RON kinase, with the IC50 value of 10 nM. and a surprising result is also obtained regarding its c-Met inhibitory activity, with the IC50 value of 12 nM. LCRF-0004 plays an important role in cancer research[1].
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LCRF-0004 | LCRF-0004 is a potent inhibitor of RON kinase, with the IC50 value of 10 nM. and a surprising result is also obtained regarding its c-Met inhibitory activity, with the IC50 value of 12 nM. LCRF-0004 plays an important role in cancer research. | |||||||||||||||||||||
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