1231929-97-7
1231929-97-7
Chemical Structure
Abemaciclib
Synonym(s): LY2835219
- CAS No.: 1231929-97-7
- Formula:C27H32F2N8
- Molecular Weight:506.59
IUPAC Name: N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine
InChIKey: UZWDCWONPYILKI-UHFFFAOYSA-N
SMILES: CC1=NC2=C(F)C=C(C3=NC(NC4=NC=C(CN5CCN(CC)CC5)C=C4)=NC=C3F)C=C2N1C(C)C
Biological Activity: Abemaciclib (LY2835219) is a selective and BBB-permeable CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.
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Abemaciclib | 99.97% | Abemaciclib (LY2835219) is a selective and BBB-permeable CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. | ||||||||||||||||||||
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Abemaciclib (Standard) | 99.94% | Abemaciclib (Standard) is the analytical standard of Abemaciclib. This product is intended for research and analytical applications. Abemaciclib (LY2835219) is a selective and BBB-permeable CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. | ||||||||||||||||||||
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Abemaciclib-d5 | Abemaciclib-d5 (LY2835219-d5) is a deuterium labeled Abemaciclib (HY-16297A). | |||||||||||||||||||||
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Abemaciclib-d8 | 99.96% | Abemaciclib-d8 is the deuterium labeled Abemaciclib. Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. | ||||||||||||||||||||
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