123291-07-6
123291-07-6
Chemical Structure
(Rac)-Sezolamide
Synonym(s): MK-927 free base; (Rac)-MK 417 free base
- CAS No.: 123291-07-6
- Formula:C11H18N2O4S3
- Molecular Weight:338.47
IUPAC Name: 4-(isobutylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
InChIKey: JFLUCCKXAYBETQ-UHFFFAOYSA-N
SMILES: O=S(N)(C1=CC(C(CCS2(=O)=O)NCC(C)C)=C2S1)=O
Biological Activity: (Rac)-Sezolamide (MK-927 (free base); (Rac)-MK 417 (free base)) is a carbonic anhydrase inhibitor (CAI) (Ki: 12.0 nM). (Rac)-Sezolamide has a topical intraocular pressure (IOP) lowering effect. (Rac)-Sezolamide can be used in glaucoma research[1].
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(Rac)-Sezolamide | (Rac)-Sezolamide (MK-927 (free base); (Rac)-MK 417 (free base)) is a carbonic anhydrase inhibitor (CAI) (Ki: 12.0 nM). (Rac)-Sezolamide has a topical intraocular pressure (IOP) lowering effect. (Rac)-Sezolamide can be used in glaucoma research. | |||||||||||||||||||||
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