123300-09-4
123300-09-4
Chemical Structure
U-80125
- CAS No.: 123300-09-4
- Formula:C42H60N8O6S
- Molecular Weight:805.04
SMILES: O=C([C@H]([C@H](CC)C)NC([C@H](C(C)C)CC([C@H](CC(C)C)NC([C@H](CC1=CN=CN1)NS(=O)(C2=CC=CC3=C(N(C)C)C=CC=C32)=O)=O)O)=O)NCC4=NC=CC=C4
Biological Activity: U80215, a dansylated peptide, is a competitive human renin inhibitor with the IC50 of 2.3 μM. U80215 shows excitation and emission maxima at 340 and 530 nm[1].
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U-80125 | U80215, a dansylated peptide, is a competitive human renin inhibitor with the IC50 of 2.3 μM. U80215 shows excitation and emission maxima at 340 and 530 nm. | |||||||||||||||||||||
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References
- [1]. Epps DE, et al. An experimental method for the determination of enzyme-competitive inhibitor dissociation constants from displacement curves: application to human renin using fluorescence energy transfer to a synthetic dansylated inhibitor peptide. Anal Biochem. 1989 Aug 15;181(1):172-81. [Content Brief]
