123408-74-2
123408-74-2
Chemical Structure
C14 Ceramide (d18:1/14:0)
- CAS No.: 123408-74-2
- Formula:C32H63NO3
- Molecular Weight:509.85
SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(CCCCCCCCCCCCC)=O
Biological Activity: C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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C14 Ceramide (d18:1/14:0) | 99% | C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research. | ||||||||||||||||||||
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C14 Ceramide (d18:1/14:0)-d7 | 99.35% | C14 Ceramide (d18:1/14:0)-d7 is the deuterium labeled C14 Ceramide (d18:1/14:0) (HY-124177A). C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research. | ||||||||||||||||||||
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C12-Ceramide | 99.82% | C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease. | ||||||||||||||||||||
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C16-Ceramide (d18:1/16:0) | 99.92% | C16-Ceramide (d18:1/16:0) is a natural small molecule activating p53 through the direct and selective binding. | ||||||||||||||||||||
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C17 Ceramide (d18:1/17:0) | 98.0% | C17 Ceramide (d18:1/17:0) (N-Heptadecanoyl-D-erythro-sphingosine) is a phospholipid internal standard. C17 Ceramide (d18:1/17:0) is used in studies of medium-chain acyl-CoA dehydrogenase deficiency (MCADD). | ||||||||||||||||||||
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C16 Ceramide (d16:1,C16:0) | 98.0% | C16 Ceramide (d16:1,C16:0) is a bioactive sphingolipid that induces ordered- and gel-phase formation and thermal stabilization of palmitoylsphingomyelin-rich domains in palmitoylphosphocholine (POPC) bilayers. C16 Ceramide (d16:1,C16:0) is found in sphingomyelins in human erythrocytes. | ||||||||||||||||||||
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C14 Ceramide | 99.91% | C14 Ceramide is an ester product. | ||||||||||||||||||||
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Octadecanoyl-L-erythro-sphingosine | Octadecanoyl-L-erythro-sphingosine is an ester product. | |||||||||||||||||||||
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C15-Ceramide | 99.73% | C15-Ceramide is an ester product. | ||||||||||||||||||||
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C16 Ceramide (d14:1/16:0) | C16 Ceramide (d14:1/16:0) is a ceramide. | |||||||||||||||||||||
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C22 Ceramide (d14:1/22:0) | C22 Ceramide (d14:1/22:0) is a ceramide. | |||||||||||||||||||||
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C18 Ceramide (d17:1/18:0) | C18 Ceramide (d17:1/18:0) is a ceramide. | |||||||||||||||||||||
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References
- [1]. Oertel S, et al. Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity. Cell Mol Life Sci. 2017 Aug;74(16):3039-3055. [Content Brief]
- [2]. Choi S, et al. Myristate-induced endoplasmic reticulum stress requires ceramide synthases 5/6 and generation of C14-ceramide in intestinal epithelial cells. FASEB J. 2018 Oct;32(10):5724-5736. [Content Brief]
