1236278-28-6

Clazakizumab Chemical Structure
1236278-28-6

Chemical Structure

Clazakizumab

Synonym(s): ALD-518; BMS-945429

  • CAS No.: 1236278-28-6
  • Formula:N/A
  • Molecular Weight:(145.234 kDa)

IUPAC Name: N-ethyl-6-(2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine-3-carboxamide

SMILES: [Clazakizumab]

Biological Activity: Clazakizumab (ALD-518; BMS-945429) is a monoclonal antibody inhibitor targeting IL-6 that binds to and blocks IL-6-mediated signaling (including trans-signaling), reducing STAT3 phosphorylation, innate immune cell infiltration, endothelial activation, and complement activation, thereby protecting the kidney from ischemia-reperfusion injury. Clazakizumab can be used in research on renal ischemia-reperfusion injury and obesity-related hypercoagulability[1][2][3][4].

Cat. No. Product Name Purity Description Pricing
HY-P99012 		Clazakizumab ≥99.0% Clazakizumab (ALD-518; BMS-945429) is a monoclonal antibody inhibitor targeting IL-6 that binds to and blocks IL-6-mediated signaling (including trans-signaling), reducing STAT3 phosphorylation, innate immune cell infiltration, endothelial activation, and complement activation, thereby protecting the kidney from ischemia-reperfusion injury. Clazakizumab can be used in research on renal ischemia-reperfusion injury and obesity-related hypercoagulability.
Pricing 
Expand Hide
loading...
/
  • /
loading...
Size Price
Stock Quantity Availability Operate
/
In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

Pricing 
Expand Hide

References

Keywords