123702-97-6
123702-97-6
Chemical Structure
Moracin O
- CAS No.: 123702-97-6
- Formula:C19H18O5
- Molecular Weight:326.34
IUPAC Name: (R)-5-(6-(2-hydroxypropan-2-yl)-5,6-dihydrobenzo[1,2-b:5,4-b']difuran-2-yl)benzene-1,3-diol
InChIKey: HMTMYIWMPJSCAZ-GOSISDBHSA-N
SMILES: CC(O)([C@H]1CC2=CC(C=C(C3=CC(O)=CC(O)=C3)O4)=C4C=C2O1)C
Biological Activity: Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Moracin O | 99.98% | Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects. | ||||||||||||||||||||
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References
- [1]. Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80. [Content Brief]
- [2]. Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96. [Content Brief]
- [3]. Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391. [Content Brief]
